EFFECTS OF BACTERIAL BIOFILMS ON RESISTANCE TO HOSPITAL DISINFECTANTS: A LITERATURE REVIEW
DOI:
https://doi.org/10.71328/jht.v8i2.74Keywords:
Biofilm, Microbial resistance, Infection control, Hospital disinfectantsAbstract
Introduction: Hospital-acquired infections are intensified by the formation of biofilms on surfaces and medical devices, making microbial elimination difficult. The effectiveness of disinfection depends on selecting the appropriate agent, its concentration, and the required exposure time. Objective: To review the literature on the impact of bacterial biofilm on resistance to hospital disinfectants, addressing biofilm formation, resistance mechanisms, and implications for infection control. Method: A narrative review of recent literature (2018–2024) was conducted in databases such as PubMed, SciELO, LILACS, and Google Scholar, using descriptors related to biofilms, hospital disinfectants, and microbial resistance. Results: Effective biofilm control requires integrating new technologies such as nanoparticles, enzymes, and UV-C light, which can overcome the protective structural barrier. Conclusion: Biofilms confer persistent resistance to disinfectants, making it essential to combine innovative technologies with strict adherence to manual protocols, supported by continuous staff training to ensure effective prevention of healthcare-associated infections.
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